It is estimated that nearly half of premature colorectal cancer (CRC) deaths nationwide are related to racial/ethnic, socioeconomic, and geographic inequalities that impact CRC screening.1 Data on health inequities and disparities is a key tool for identifying and addressing these barriers in vulnerable populations, thus improving health equity.
Black and African American
- Black individuals have the second highest rate of CRC mortality compared to all other races and ethnicities4
- Compared to White individuals and individuals of all races combined, Black individuals are less often diagnosed at stages I and IIa,b and are more often diagnosed at regional and distant stages4
- 5-year survival among all people diagnosed with CRC at distant stages is 14% vs 91% when diagnosed at stages I or II4,a,b
Hispanic and Latino
- Cancer is the leading cause of death among Hispanic individuals, accounting for 20% of deaths. Cancer is the second leading cause of death in White individuals5
- Among Hispanic males, CRC is the second leading cause of new cancers and cancer-related death. Among White men, CRC is the third leading cause of new cancers and cancer-related death5
- Adherence to CRC screening varies by sex and region or country of origin5
- Compared to Non-Hispanic White individuals, cancer is less commonly diagnosed at a local or regional stage5
American Indian/Alaska Native
- American Indian/Alaska Native individuals have a 51% higher risk of cancer death compared to White individuals (this is not specific to CRC)4
- American Indian/Alaska Native individuals have the highest incidence and are more likely to die of CRC compared to all other races4
- The rate of incidence among American Indian/Alaska Natives varies by US region6
Incidence of CRC by Race, Ethnicity and Sex in United States from 2015-2019
Mortality of CRC by Race, Ethnicity and Sex in United States from 2016-2020
- Both CRC incidence and mortality were highest among American Indian/Alaskan Natives7
- Incidence and mortality vary widely across populations7
Footnotes
- Based on people with CRC diagnosed between 2013 and 2019.
- Per American Joint Committee on Cancer’s (AJCC) staging system: Localized = stage I, IIa, IIb. Regional = stage IIc and III. Distant = stage IV.8
List of definitions
AJCC: American Joint Committee on Cancer; CRC: colorectal cancer; US: United States.
References
- Jemal A, Siegel RL, Ma J, et al. Inequalities in premature death from colorectal cancer by state. J Clin Oncol. 2015;33(8):829-835.
- American Cancer Society. Cancer facts & figures for African American/Black People 2022-2024. Accessed May 14, 2024. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/cancer-facts-and-figures-for-african-americans/2022-2024-cff-aa.pdf
- American Cancer Society. Colorectal cancer higher in African Americans, rising in younger people. Accessed May 14, 2024. https://www.cancer.org/cancer/latest-news/colorectal-cancer-rates-higher-in-african-americans-rising-in-younger-people.html
- Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024;74:12-49.
- American Cancer Society. Cancer facts & figures for Hispanics/Latinos 2021-2023. Accessed May 14, 2024. www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/cancer-facts-and-figures-for-hispanics-and-latinos/hispanic-latino-2021-2023-cancer-facts-and-figures.pdf
- Melkonian SC, Weir HK, Jim MA, et al. Incidence of and trends in the leading cancers with elevated incidence among American Indian and Alaska Native populations, 2012-2016. Am J Epidemiol. 2021;190(4):528-538.
- Siegel RL, Miller KD, Wagle NS, et al. Colorectal cancer statistics, 2023. CA Cancer J Clin. 2023;73(3):233-254.
- American Cancer Society. Colorectal cancer stages Accessed May 14, 2024. https://www.cancer.org/cancer/types/colon-rectal-cancer/detection-diagnosis-staging/staged.html#how-is-the-stage-determined