For patients
Oncodetect™ Molecular Residual Disease test

Clear and accurate results to help you stay a step ahead of your cancer

The Oncodetect Molecular Residual Disease (MRD) test looks for tiny fragments of cancer DNA in your blood and can detect cancer recurrence more than 2 years earlier than traditional cancer surveillance methods.1
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Outcome

Detects fragments of DNA from your tumor to help you understand your risk of recurrence and monitor response to therapy or surgery.1

Is this test right for you?

The Oncodetect MRD test is for patients who have been diagnosed with solid cancers.*

Sample type

Initial test analyzes your blood, along with tumor tissue from your surgery or biopsy. Monitoring tests require only a blood sample.
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Answering your biggest questions

Is my cancer gone? Is it responding to treatment? Could it come back?

You are one-of-a-kind — and so is your tumor. That’s why the Oncodetect MRD test looks for circulating tumor DNA (ctDNA) shed by your specific tumor. The results can help you and your health care provider make more informed decisions about your treatment path.

Detect and measure ctDNA levels to see if your cancer is gone after surgery1,2

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Monitor response to surgery or adjuvant therapy, such as chemotherapy1,2

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Determine whether your cancer is likely to come back1,2

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Is this test right for me?

If you’ve been diagnosed with a solid cancer,* the Oncodetect MRD test can help guide chemotherapy decisions, detect early recurrence, and monitor your response to therapy.1,2 Read our helpful discussion guide for more details, including questions you may want to ask your oncologist.

An estimated 3 million patients in the United States alone could benefit from MRD testing.†

Insights to help you plan your next steps with confidence

The Oncodetect MRD test is highly sensitive, so it’s able to detect even small fragments of ctDNA shed into the bloodstream from your tumor.1 Adding it to your surveillance plan can help you and your doctor make more timely treatment decisions.

Earlier answers

MRD testing can detect evidence of cancer up to 2 years earlier than imaging, giving you more time to plan your treatment path.1
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Personalized results

By tracking up to 200 gene variants specific to your tumor, the Oncodetect MRD test grants more opportunities to detect ctDNA in the blood.1,3
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See how the Oncodetect MRD test can help guide your treatment path

Stay a step ahead of your cancer with Oncodetect Molecular Residual Disease.
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How does the test work?

First, we analyze your tumor tissue to create a personalized profile around your cancer’s unique DNA. Then we look for fragments of that DNA in your blood to find out if your cancer is still present or if it is likely to recur. 

Have questions?

Call us at +1 888-662-6897.

References and footnotes

  1. Diergaarde B, Young G, Hall DW, Mazloom A, Costa G, Subramaniam S, Palomares M, Garces J, Baehner FL, Schoen RE; and other members of the Exact Sciences MRD Group. Circulating tumor DNA as a marker of recurrence risk in Stage III colorectal cancer: The α‐CORRECT study. Journal of Surgical Oncology.
  2. Centers for Medicare & Medicaid Services, Medicare Coverage Database. LCD—MolDX: Minimal Residual Disease Testing for Cancer. Accessed January 21, 2025. https://www.cms.gov/
  3. Santonja et al. EMBO. 2023. https://www.embopress.org/doi/full/10.15252/emmm.202216505
  4. The test has been validated in patients with stage II-IV colorectal cancer and Exact Sciences is currently pursuing applications in additional disease ontologies.
  5. Internal estimate for addressable patient populations based on solid tumors amenable to MRD testing.


    This test was developed, and its performance characteristics determined by Genomic Health, Inc. The Oncodetect test was clinically validated in colorectal cancer patients with stage II-IV disease. Performance characteristics may not apply in tumor types not included in this test’s clinical validation. The test has not been cleared or approved by the US Food and Drug Administration. The test has been validated as a Laboratory Developed Test per institutional and applicable CLIA regulation (CLIA# 03D2048606) and College of American Pathology (CAP# 8869063) as qualified to perform high complexity clinical laboratory testing.