Exact Sciences logo
United States
Choose your country

Select to view the solutions available in your location.

Select
Cancel
Login
Patient login

Track orders, get results, manage personal information, and more.

Provider login

Order tests, track orders, get results, and more.

CLINICAL STUDIES

Learning you may have or be at risk for cancer is hard. But getting ahead of it is becoming easier. Exact Sciences has a vision to help you discover and eradicate cancer early through one-of-a-kind tests that screen for cancer or help identify targeted treatments for your specific cancer.

Exact Sciences has developed a range of tests that can catch cancer before you know it or give you important information about the genes responsible for your diagnosed cancer. With this information in hand, you and your doctor can confidently choose a treatment path that may be most effective and personalized for you.

Right now, these tests focus on colorectal and breast cancers. But our scientific teams are also busy researching more cancers and developing multi-cancer testing to help many more people in the future. We're pleased to share some of our current clinical studies that will allow us to bring great new tests to patients.

At Exact Sciences, we conduct a range of clinical studies to rigorously assess the safety and performance of our tests in order to detect cancer earlier and guide optimal treatment.

We're pleased to highlight below some of our current clinical study efforts.

CURRENTLY ENROLLING STUDIES

COLORECTAL CANCER
SCREENING

DIAGNOSED
COLORECTAL CANCER

LIVER CANCER
SCREENING

MULTI-CANCER
SCREENING

COMPASS

Exact Sciences, Mayo Clinic, University of Utah, American Cancer Society, and Fight Colorectal Cancer (Fight CRC) are working together on a clinical study to evaluate what impact an educational video about colorectal cancer screening has on patients completing their colorectal cancer screenings. Adults ages 45 to 70 who are scheduled for a primary care appointment, at average risk for colorectal cancer (CRC), and are due for CRC screening may be eligible to enroll. In addition to viewing the video, participants will be asked to complete several surveys over a 6-year study period.  

For more information, refer to the link below.  

NOW ENROLLING

VOYAGE

Exact Sciences and Mayo Clinic are working together on a clinical survey study to gather long-term health information from people who have been prescribed the Cologuard® test. Participants who receive a Cologuard test may be invited to participate by mail. Participants will be asked to complete a baseline health questionnaire survey (T0), a 1-year follow-up questionnaire survey (T1), allow future contact for additional surveys, and may allow access to medical records as available.

For more information, refer to the link below.

NOW ENROLLING

CORRECT-I

Exact Sciences is conducting an international, observational study called CORRECT-I, enrolling Stage II and Stage III colorectal cancer patients. The aim of this study is to collect multiple blood samples over 5 years to evaluate if an investigational blood test is able to predict colorectal cancer recurrence by detecting minimal residual disease (MRD). Research sites are enrolling participants in Israel, Japan, Italy, Spain, and the United Kingdom.

NOW ENROLLING

CORRECT-II

Exact Sciences, National Surgical Adjuvant Breast and Bowel Project (NSABP) and Fight Colorectal Cancer (Fight CRC) are working together on an observational study called CORRECT-II, enrolling Stage II and Stage III colorectal cancer patients. The aim of this study is to collect multiple blood samples over 5 years to evaluate if an investigational blood test is able to predict colorectal cancer recurrence by detecting minimal residual disease (MRD). 

For more information, refer to the clinicaltrials.gov link below. To find a participating site near you, please contact the NSABP Department of Site and Study Management at 1-800-270-3165 or by e-mail at industry.trials@nsabp.org.

NOW ENROLLING

ALTUS

Exact Sciences is currently conducting a clinical study called ALTUS, which is enrolling patients who are at increased risk for a type of liver cancer called hepatocellular carcinoma (HCC). In the study, participants will have radiology exams to check if HCC is developing and also provide blood samples for the Oncoguard®  Liver blood test. The goal of the ALTUS study is to determine how well the Oncoguard Liver blood test can detect HCC in this patient population.

For more information, refer to the link below.

NOW ENROLLING

FALCON REGISTRY

Exact Sciences is conducting the Falcon Registry study, a multi-site study to collect real-world evidence from up to 25,000 patients being tested with the Exact Sciences MCED test—a multi-cancer early detection (MCED) test. The Falcon Registry study aims to collect data about the course of care and outcomes for patients who are tested with the Exact Sciences MCED test under development, as well as any impact the testing may have on patient anxiety. The study will also gather data from a set of up to 50,000 patients who have received only single-cancer standard-of-care screening and will compare these data to those who were tested with the Exact Sciences MCED test. Those who enroll in the study will be offered the Exact Sciences MCED test once a year for up to three years and data will be collected for up to 5 years.

For more information, refer to the link below.

NOW ENROLLING

Completed Studies

Detecting Cancers Earlier Through Elective mutation-based blood Collection and Testing (DETECT-A) Study

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention.

Download Summary


Are you interested in participating in a Clinical Study? Here’s what you can do and what you can expect:

Step 1

Reach out to your doctor to ask about a clinical study that seems related to your condition. Alternatively, your provider may suggest you participate in a specific clinical study that could help treat your condition.

 Study staff will ask you a few questions to see if you meet the requirements to join the study.

Step 2

If you meet the eligibility requirements, a team of medical professionals will thoroughly discuss the study with you, give you time to ask questions, and review the informed consent form. Once you feel comfortable and have all your questions answered, you’ll provide written permission to start your participation in the study.

Step 3

Arrive at the clinic for your first visit! After that, you will continue to come in for visits according to the clinical study schedule.