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The Riskguard® test helps you help your patients

The Riskguard® test is an assessment tool that can help uncover hereditary cancer risk. The actionable results can help you better understand your patients’ risk level and management options supporting personalized care.

Request the Riskguard test

Who can the Riskguard test help?

A three-generation family is happily sitting in a living room discussing the grandmother’s results.

Patients without cancer

The Riskguard test helps inform the risk stratification for patients who have a family history of cancer by identifying variants in clinically actionable cancer-associated genes, from which you can form a customized path.

Customize a prevention path

  • Lifestyle changes
  • Screening programs
  • Risk-reducing medication
  • Risk-reducing surgeries
An older adult woman embraces her daughter on the sofa as she gazes out the window.

Patients with cancer

The Riskguard test can assist with informing an individualized plan for your patients who have been diagnosed with cancer. Knowing about certain gene variants can help you select optimal treatment.1-6

Inform optimal treatment

  • Surgical options
  • Increased surveillance
  • Targeted therapies

More ways to personalize patient care

Add the Riskguard test to our OncoExTra™ genomic profiling test to help increase the number of patients with advanced or metastatic cancer that are eligible for targeted therapies.

Pair the Riskguard test with our Oncotype DX Breast Recurrence Score® test to help inform a more comprehensive treatment plan for newly diagnosed ER+/HER2- breast cancer.

Customize a prevention path

  • Lifestyle changes
  • Screening programs
  • Risk-reducing medication
  • Risk-reducing surgeries

Inform optimal treatment

  • Surgical options
  • Increased surveillance
  • Targeted therapies

More ways to personalize patient care

Add the Riskguard test to our OncoExTra™ genomic profiling test to help increase the number of patients with advanced or metastatic cancer that are eligible for targeted therapies.

Pair the Riskguard test with our Oncotype DX Breast Recurrence Score® test to help inform a more comprehensive treatment plan for newly diagnosed ER+/HER2- breast cancer.

The Riskguard test checks for genes across 10 cancer types

Colorectal, Breast, Prostate, Pancreatic, Ovarian, Endometrial, Skin, Gastric, Kidney, Endocrine
Colorectal, Breast, Prostate, Pancreatic, Ovarian, Endometrial, Skin, Gastric, Kidney, Endocrine
VIEW GENE LIST 

We keep it simple and actionable

We want our results to be simple yet powerful. That’s why we only report on variants in genes you can do something about based on guidelines and published literature. We provide easy-to-understand results that providers and patients can use for personalized care planning. Just the information you need, none of the stuff you don’t.

A minimal illustration of a results report with three highlighted items: summary findings, results, and care points.

Complete access to our premium customer support before, during, and after testing

On-Demand
Customer Care

Call our customer care team for general questions at 1-866-662-6897. You can request the Riskguard test kits and ask about billing, ordering, and how to access results.


Call Customer Care 

GENETIC SUPPORT
FOR YOUR PATIENTS

Our customer care team can help answer your patients’ questions about the Riskguard test and the testing process. We can also connect them with an independent genetic counselor,* who will take a more detailed family history and provide more in-depth information.

Genetic support
for you

Ask customer care to connect you with one of our genetic counselors for an in-depth consultation. We can help you understand and interpret Riskguard test results, including medical management options for your patient.

PATIENT EDUCATION ON DEMAND

Want to help your patients learn more about the Riskguard test? Genetic counselor Brandie Leach breaks down who the test is for, what the testing process is like, and how the results could inform your patient's risk.

Billing is easy when you have a support team like ours.

Coverage for eligible patients including Medicare and commercial insurance

Specialized support for billing insurance and prior authorization

Flexible payment options for patients


View Billing and Coverage 

Let’s get started

Clinical testing collection kit box with the Riskguard(TM) Hereditary Cancer Test and Exact Sciences logos on the cover.

REQUEST THE RISKGUARD TEST

Call customer care at 1-866-662-6897 to request our Riskguard test kits. We can send blood or saliva test kits right to your office, or we can send a convenient at-home saliva test kit directly to your patient's address.†


Call to request the test 

SUBMIT LAB ORDER

Download order form below and fax to 1-715-406-4175. If you are collecting a sample in clinic, include a copy of the order form in the specimen kit.


Download order form 

OR

Submit an electronic order through the Exact Sciences Provider Hub.

Submit order 

The Riskguard(TM) test order form.
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ACCESS RESULTS

You can view your patients’ results on our Exact Sciences Provider Hub. Patients can access their results with their own Exact Sciences account. If they have additional questions, we can connect them to an independent genetic counselor.*


Access patient results 

PROVIDER RESOURCES

Exact Sciences Provider Hub

Submit orders, download forms, access test results and more.


LOG IN OR CREATE ACCOUNT 

Patient Case Studies

See how adding the Riskguard test can give you and your patient powerful information.


RISKGUARD + ONCOTYPE DX®  

RISKGUARD + ONCOEXTRA® 

Patient Education Video

Learn more about how the Riskguard test can help guide treatment and prevention.


WATCH VIDEO 

Billing and Coverage

We're here to help. Our support team can help your patients navigate the insurance coverage process.


Download info card 

EXPLORE COST & COVERAGE INFO 

Gene List

Riskguard is a multigene test that may impact clinical decision-making in common cancer types.


Download 

Patient Screening Tools

See which risk factors and diagnoses make the Riskguard test a fit for your patient.


Download 

FREQUENTLY ASKED QUESTIONS

More ways to personalize patient care

Oncotype DX

Provides individualized genomic insights to help customize treatment for patients with HR+, HER2-early-stage breast cancer.

OncoExTra

Offers ultra-comprehensive genomic profiling to aid in therapy selection for patients with advanced disease.

Cologuard RX only

Screens average-risk individuals who are 45 years and older for colon cancer (Rx Only).

WE’RE HERE FOR YOU

With questions about ordering the Riskguard test, insurance billing and payment options, checking results, or getting connected with a genetic counselor, call us at 1-866-662-6897 or email us at riskguard@exactsciences.com.


Call Us
Email Us

* There may be patient cost associated with independent genetic counseling services.

† Riskguard test kits are provided at no charge and are to be used only with the Riskguard test.

‡ Data on file

The Exact Sciences Riskguard test was developed, and its performance characteristics validated by an Exact Sciences laboratory following College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) regulations. The test is performed in Marshfield, WI at PreventionGenetics LLC, a wholly owned subsidiary of Exact Sciences. PreventionGenetics is accredited by CAP, certified under CLIA regulations, and qualified to perform high-complexity clinical laboratory testing. It has not been cleared or approved by the US Food and Drug Administration or other notified regulatory authority. Genomic Health, Inc., an Exact Sciences company, is the billing entity for Riskguard.