The Riskguard^® test IS knowledge that gives you power over your health

The Riskguard^® test is an assessment tool that can help uncover hereditary cancer risk. With just a simple blood or saliva sample, it checks for hereditary genetic changes that can cause an increased risk for certain cancers.

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Get to know the Riskguard test genetic counselor Brandie Leach breaks down who the test is for, what the testing process is like, and how the results could inform your risk.

Who can the Riskguard test help?

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If you have a family history of cancer, the Riskguard test can help you know if you have inherited changes in your genes that are linked to cancer, and may inform risk-reducing strategies.

If you have been diagnosed with cancer, the Riskguard test can help you know about hereditary genetic changes in your genes that can assist you and your provider in making a treatment path customized to you.

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How can the Riskguard test help?

Tailored treatment and prevention journeys

Have peace of mind knowing you and your provider can form better treatment and prevention journeys guided by genetics.^1-6

Easy-to-understand results

Receive easy-to-understand results via your Exact Sciences patient account, with potential next steps for a personalized care plan.

We work hard to make understanding results easy

Sometimes receiving results can be complicated. That's why we've made our results easy to understand, and our dedicated support team will be there every step of the way to walk you through the process

Negative white icon on dark gray background

A negative result means you’ll have powerful information.

Knowing your result is negative may do more than put you at ease, it could also mean less frequent screenings and avoiding unnecessary treatment.^7-9 You and your provider can use this information, along with your family history and other factors, to decide next steps.

A positive result does not mean you’ll develop cancer.

It means you may be at a higher risk than average, and we’re here to support you and your provider as you create a personalized prevention or treatment plan. We’ll also let you know about future changes to your results or new research that could optimize your care path.

Riskguard checks for genes across 10 cancer types

Colorectal, Breast, Prostate, Pancreatic, Ovarian, Endometrial, Skin, Gastric, Kidney, Endocrine

VIEW GENE LIST

Not all questions have to mean an office visit

Our premium customer service is just a phone call away, and we can answer questions big and small before, during, and after testing.

On-Demand Customer Care

Call our customer care team at 1-866-662-6897 with general questions about the Riskguard test, billing, insurance coverage, and flexible payment plans.

Call Customer Care

Genetic Counselors

Ask customer care to connect you with an independent genetic counselor for an in-depth telehealth consult.* They can help review your family history, assess your cancer risk, understand your Riskguard test results, and assist with next steps.

How it works

See if the Riskguard test is a fit

First, speak with your provider to determine if the Riskguard test is a good fit for you. Our customer care team is available if you have additional questions about billing, insurance, payment plans and more.

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Take the test

The Riskguard test will need to be ordered by your provider. You may provide a blood or saliva sample in your provider’s office, or we can ship one of our convenient at-home saliva test kits directly to you.

Get your results

Your provider will review your results with you and design a customized care plan. You can also access your results online via your Exact Sciences patient account. For a more in-depth consult, we can connect you to an independent genetic counselor.*

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You have enough things to worry about, insurance coverage shouldn’t be one of them.

Coverage for eligible patients including Medicare and commercial insurance

Specialized support for billing insurance and prior authorization

Flexible payment options

View Billing and Coverage

PATIENT RESOURCES

FREQUENTLY ASKED QUESTIONS

How much does this test cost?
Does a doctor have to order my test? Or can I order a test for myself?
How long does it take to get my results back?

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WE’RE HERE FOR YOU

With questions about ordering the Riskguard test, insurance billing and payment options, checking results, or getting connected with a genetic counselor, call us at 1-866-662-6897 or email us at riskguard@exactsciences.com.

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*There may be a patient cost associated with independent genetic counseling services.

^†Data on file

References

1 Geyer CE Jr, Garber JE, Gelber RD, et al; OlympiA Clinical Trial Steering Committee and Investigators. Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer. Ann Oncol. 2022;33(12):1250-1268.

2 Hussain M, Mateo J, Fizazi K, et al; PROfound Trial Investigators. Survival with olaparib in metastatic castration-resistant prostate cancer. N Engl J Med. 2020;383(24):2345-2357.

3 Golan T, Hammel P, Reni M, et al. Maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer. N Engl J Med. 2019;381:317-327.

4 Ledermann J, Harter P, Gourley C, et al : Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet Oncol 2014;15:852-861.

5 Domchek SM, Friebel TM, Singer CF, et al. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA. 2010;304(9):967-975.

6 Ladabaum U, Wang G, Terdiman J, et al. Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Ann Intern Med. 2011;155(2):69-79.

7 Robson et al N Engl J Med. 2017; 377:523-533

8 Tischler et al Ann Intern Med. 2019 Dec 17;171(12):925-930

9 Kurian et al J Clin Oncol. 2011 Dec 1;29(34):4505-9

The Exact Sciences Riskguard test was developed, and its performance characteristics validated by an Exact Sciences laboratory following College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) regulations. The test is performed in Marshfield, WI at PreventionGenetics LLC, a wholly owned subsidiary of Exact Sciences. PreventionGenetics is accredited by CAP, certified under CLIA regulations, and qualified to perform high-complexity clinical laboratory testing. It has not been cleared or approved by the US Food and Drug Administration or other notified regulatory authority. Genomic Health, Inc., an Exact Sciences company, is the billing entity for Riskguard.

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The Riskguard^® test IS knowledge that gives you power over your health

Who can the Riskguard test help?